See https://journals.asm.org/doi/10.1128/mSphere.00056-21 as a starter but there are many more. What can't be discounted is some fraction of vaccinated already had been infected. The vaccines were administered without bothering to screen for previous infections. If so the vaccine 'efficiency' is hidden by the immunity from infection.
The next question really is related to boosters. If OAS has arrived, the boosters may be harmful in some. The effort to mass vaccinate now seems ill advised and those vaccinated are now at some risk. Hopefully, having a breakthrough infection could be a good thing, but if OAS is at work, perhaps not. An awful experiment is now in progress.
It could be original antigenic sin in the vaccinated.
I would love to know more about it, can you explain? I just read the definition of OAS, but I do not see how it applies, so can you clarify?? Thanks
See https://journals.asm.org/doi/10.1128/mSphere.00056-21 as a starter but there are many more. What can't be discounted is some fraction of vaccinated already had been infected. The vaccines were administered without bothering to screen for previous infections. If so the vaccine 'efficiency' is hidden by the immunity from infection.
The next question really is related to boosters. If OAS has arrived, the boosters may be harmful in some. The effort to mass vaccinate now seems ill advised and those vaccinated are now at some risk. Hopefully, having a breakthrough infection could be a good thing, but if OAS is at work, perhaps not. An awful experiment is now in progress.
Yep, good points and thanks for the link, I will read it later today.