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Igor Chudov's avatar

ask your friend to measure toxicity to immune cells, CD4, CD8, monocytes, etc

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Ashmedai's avatar

I don't know if NIH policy allows for changing the study in "post production" :)

The way she described (at least how I understood lol), they were seeding cells in vitro with different concentrations of diff variants etc to see relationship toxicity-quantity/viral load

Checking effects on populations of CD4/8 etc. probably be a wee bit more difficult, hard to simulate the bioenvironmental factors that guide immunological mechanisms in vitro unlike a cell line you can just 'inject' with something in a petri dish and see if it is poisonous to the cells which should usually roughly translate in anatomical environment more or less. I'm pretty sure she dropped a line about cells that aren't dying from viral infection (usually just going a bit hungry as virus competes with cellular enzymes etc for cell resources like ribosomes etc) don't release the same sort of immunologically triggering signals etc. though.

Of course, that's allegedly why there's a CDC/NIH in the first place, to do sophisticated specialized research.

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Igor Chudov's avatar

very exciting!

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