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Neutron Flux's avatar

Turtles All The Way Down. The scammers don't use saline in the control groups; they use prior versions of the latest updated snake oil shot so any adverse events appear similar for the new drug group vs "placebo"!

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Satan's Doorknob's avatar

I haven't read "Turtles" but have read enough about all the deceptive tricks used in setting up a clinical trial, reporting on it, etc. The same dodge you describe was deliberately done (I think) in the Vioxx trials; they knew it caused heart issues and deliberately compared it against a high dose of some other medication for the comparator. The gambits are limitless and a book should be written about them. Probably already has been. Kendrick's "Dcotoring Data" is a favorite.

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Neutron Flux's avatar

Kendrick is awesome. He stands up to the statin scam too.

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