I have wondered the same thing...there has been zero reporting that I can find on the severity of Omicron in the unvaccinated who have contracted it, but plenty about how vaccinated people are having less severe cases, thanks to vaccination. It's nonsensical. I can't tell if governments are deliberately leaving out that information so as not to freak people out because unvaccinated are severely ill, or to hide the fact that unvaccinated are less severely ill than vaccinated....
omicron preferentially infecting the vaccinated is basically the definition of ADE no? Just because the ADE results in only enhancement of a mild disease, doesn't make it any less of an ADE.
If this is the case and omicron really does preferentially infect the vaccinated as opposed to to the non-vaccinated recovered and non-vaccinated uninfected, then the only logical mechanism for this is that the vaccinated have something about them that assists the infection by omicron, which is probably non-neutralizing antibodies coupled with bypassed neutralizing antibodies geared towards non-Omicron spike proteins (whereas the non-vaccinated recovered would also have antibodies to the nucleotide proteins which seem to be conserved and thus the antibodies to those retain some effectiveness in fighting off infection).
If this is even remotely the case the world dodged a MASSIVE BULLET if omicron is milder, because if it was as severe (or worse) than say Delta, Alpha or the wildtype Wuhan strain, but still as reportedly transmissible as omicron is now then highly vaccinated societies and their followers in the developing world (which would have between say 15-40% of their adult population vaccinated) would REALLY see overwhelmed hospitals as you postulated in an earlier post and we would enter into an even worse dystopia than the one we are currently experiencing (since the powers that be aren't going to admit that what they did was a mistake, but shift the blame elsewhere and double-down on their measures...at least until there was enough anger among (now rightly) fearful vaccinated persons that that they boot them out of office (via election or protest), but there is no guarantee that those who come after won't decide that even harsher measures aren't the way to go (basically importing the North Korea-model of society, governance and travel...and then pumping it full of steroids)
Do you know of any interesting ADE data?
All I know is that Omicron preferentially infects the vaxxed. Is there something else interesting?
There is not much information on severity in vaxxed vs unvaxxed. I wonder if this is just an accident or?
I have wondered the same thing...there has been zero reporting that I can find on the severity of Omicron in the unvaccinated who have contracted it, but plenty about how vaccinated people are having less severe cases, thanks to vaccination. It's nonsensical. I can't tell if governments are deliberately leaving out that information so as not to freak people out because unvaccinated are severely ill, or to hide the fact that unvaccinated are less severely ill than vaccinated....
There is little death data that I am aware of, but they could break down hospitalizations by vaccination. Denmark already has 77 hospitalized.
omicron preferentially infecting the vaccinated is basically the definition of ADE no? Just because the ADE results in only enhancement of a mild disease, doesn't make it any less of an ADE.
If this is the case and omicron really does preferentially infect the vaccinated as opposed to to the non-vaccinated recovered and non-vaccinated uninfected, then the only logical mechanism for this is that the vaccinated have something about them that assists the infection by omicron, which is probably non-neutralizing antibodies coupled with bypassed neutralizing antibodies geared towards non-Omicron spike proteins (whereas the non-vaccinated recovered would also have antibodies to the nucleotide proteins which seem to be conserved and thus the antibodies to those retain some effectiveness in fighting off infection).
If this is even remotely the case the world dodged a MASSIVE BULLET if omicron is milder, because if it was as severe (or worse) than say Delta, Alpha or the wildtype Wuhan strain, but still as reportedly transmissible as omicron is now then highly vaccinated societies and their followers in the developing world (which would have between say 15-40% of their adult population vaccinated) would REALLY see overwhelmed hospitals as you postulated in an earlier post and we would enter into an even worse dystopia than the one we are currently experiencing (since the powers that be aren't going to admit that what they did was a mistake, but shift the blame elsewhere and double-down on their measures...at least until there was enough anger among (now rightly) fearful vaccinated persons that that they boot them out of office (via election or protest), but there is no guarantee that those who come after won't decide that even harsher measures aren't the way to go (basically importing the North Korea-model of society, governance and travel...and then pumping it full of steroids)